June 17, 1997
Web posted at: 10:46 p.m. EDT (0246 GMT)
ATLANTA (CNN) -- A byproduct of chlorination in drinking
water has been linked to cancer in rats, leading the
government to investigate adverse effects of water
disinfectants.
A chemical byproduct called MX develops from organic
compounds in the chlorinated drinking water, and Finnish
researchers found that rats exposed to high levels of MX got
several types of cancer.
"The new study is showing that yet another one of the common
byproducts of using chlorine in our drinking water appears to
be linked to cancer," said Erik Olson of the National
Resources Defense Council.
The researchers report their findings in the Journal of the
National Cancer Institute, to be published Wednesday.
"Although these findings cannot be extrapolated to humans, MX
should be studied as a candidate risk factor" in the
consumption of chlorinated drinking water, the study says.
Scientists in the National Toxicology Program, under the
auspices of the National Institutes of Health, are launching
a two-year study of MX and other chlorination byproducts.
They want to see how MX -- at various low doses -- affects
the occurrence of cancer in rats and mice.
MX a potent carcinogen in rats
In the Finnish study, government and university scientists
fed groups of 50 rats three different dosages of MX in
drinking water. The 50 rats in a fourth group received no MX
and were maintained as a control.
At the end of two years, the rats were killed and their body
tissues were analyzed.
Among rats receiving the highest doses of MX, more than half
developed cancer or tumors of the thyroid, compared to about
22 percent in the control rats. The MX rats also developed
cancer of the lungs, skin, breast, liver and pancreas.
"MX is a potent carcinogen in both male and female rats, and
it causes tumors at doses that are not overtly toxic to
rats," the Finnish researchers reported.
The cancer potency of MX is up to 170 times greater than some
other chemical byproducts in chlorinated water, such as
chloroform and bromodichloromethane, according to Dr. Ronald
Melnick of the National Institute of Environmental Health
Sciences.
However, he said the Finnish researchers used a dosage of MX
thousands of times higher than what is present in the typical
U.S. water system that is treated with chlorine. He estimated
that MX at the doses studied in Finland would cause about two
cancers per 1 million people over a lifetime.
Benefits of chlorine outweigh risks
Melnick said although MX should be studied, there should be
no move to remove chlorination from public drinking water.
Chlorination controls many waterborne diseases, including
typhoid fever, cholera and dysentery. When chlorination was
stopped recently in Peru, for instance, there was a cholera
epidemic of 300,000 cases.
More than 90 percent of drinking water in the United States
is treated to remove harmful bacteria, and the benefits far
outweigh the known cancer risks, scientists say.
But MX levels in U.S. drinking water are not usually
monitored routinely, and Melnick said that is needed.
"We want our water to be as safe as possible, but in a
chemical treatment such as this, it is impossible to have
absolute zero risk," he said.
The presence of MX in drinking water may be controlled by
filtering the water before the chlorine is added, Melnick
said. Such filtering would remove the organic compounds that
chlorine acts on to produce MX.
For those wishing to try to lessen any risk at home, experts
say a good activated charcoal filter can trap some of the
potential carcinogens in tap water.
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